Through the Interdisciplinary Graduate Education Program (IGEP) in Infectious Diseases, CeZAP works with the Graduate School and academic colleges to help train graduate students with a broad scientific perspective on infectious diseases by providing interdisciplinary research training opportunities that include a cohesive but diverse environment, infectious disease seminar series, journal club, workshops, social events, etc.
CeZAP will also provide opportunities for undergraduate students to conduct research that connects labs from different disciplines. In addition to training students to conduct basic and mechanistic research, CeZAP will also partner with industries to train a new generation of infectious disease professionals focusing on translational and applied research.
Through the Interdisciplinary Graduate Education Program (IGEP) in Infectious Diseases, CeZAP works with the Graduate School and academic colleges to help train graduate students with a broad scientific perspective on infectious diseases by providing interdisciplinary research training opportunities that include a cohesive but diverse environment, infectious disease seminar series, journal club, workshops, social events, etc. CeZAP will also provide opportunities for undergraduate students to conduct research that connects labs from different disciplines. In addition to training students to conduct basic and mechanistic research, CeZAP will also partner with industries to train a new generation of infectious disease professionals focusing on translational and applied research.
Distinguished Speaker Seminar Series in Infectious Diseases
Jonathan Auguste, and Nisha Duggal
The Center for Emerging, Zoonotic and Arthropod-borne Pathogens (CeZAP) introduces the CeZAP Distinguished Speaker Seminar Series in Infectious Diseases. This university wide seminar series at Virginia Tech invites outstanding scientists nationally to give presentations to CeZAP and broader university community on topics of current interest in the broad area of infectious diseases. Diversity of seminar topics is essential to meeting the purpose of the Distinguished Speaker Seminar Series in Infectious Diseases. Each spring, nominations for nationally distinguished speakers for the seminar series for the following academic year will be solicited from CeZAP affiliated faculty. The seminar coordinators (Drs. Jonathan Auguste and Nisha Duggal) will coordinate the selection of speakers, and the CeZAP faculty nominators will serve as the host for the national speakers. We expect to host at least one nationally distinguished speaker each month, and the remaining speakers will feature our own CeZAP affiliated faculty.
SPRING 2022 SCHEDULE
Seminar Date & Time:
Tuesdays at 12:30pm starting January 18, 2021
January 18, 2022:
Jaline Gerardin, Ph.D. Assistant Professor, Northwestern University
"Mathemathical modeling to inform malaria policy"
Host: Lauren Childs, Ph.D.
January 25, 2022:
Nick W. Ruktanonchai, Ph.D. Assistant Professor, Department of Population Health Sciences, VA-MD College of Veterinary Medicine
"Using human mobility data to predict and control infectious disease spread" Recorded Video
February 1, 2022:
Andrew Lowell Ph.D. , Assistant Professor, Department of Chemistry, and Anne M. Brown Ph.D. Assistant Professor, Department of Biochemistry
"Overcoming AMR through antibiotic redesign: Coupling computational and experimental science" Recorded Video
February 8, 2022:
Ben Hause, Ph.D. Assistant Professor, South Dakota State University
"Metagenomic sequencing for virus discovery and characterization"
Host: Kevin Lahmers, Ph.D. Recorded Video
February 15, 2022:
Kim Seed, Ph.D. Assistant Professor, Department of Plant and Microbial Biology, UC Berkeley
"Fighting with phages: how epidemic Vibrio cholerae defends against viral attack"
Host: Bryan Hsu, Ph.D.
February 22, 2022:
Robyn Klein, Ph.D. The Robert E. and Louise F. Dunn Distinguished Professor of Medicial Sciences, Director of the Center for Neuroimmunonology and Neuroinfectious Diseases, and Professor of Medicine, Pathology and Immunology, and Neurosciences, Washington University School of Medicine
"Emerging RNA viruses and neurologic sequelae" Recorded Video
Host:Kylene Kehn-Hall, Ph.D.
March 1, 2022:
Jeff Freeman, Ph.D. Senior Professional Staff in the National Health Mission Area of the Johns Hopkins University Applied Physics Lab
Title: Evolution of the national COVID-19 response: Lessons learned and a way forward"
Host: Cassidy Rist, Ph.D.
March 15, 2022:
Xinhua Chen, Ph.D. Assistant Professor of Medicine, Beth Israel Deaconess Medical Center
Title: "C.difficile Infectious --- What Remains Difficult?"
Host: Xin Luo, Ph.D.
March 22, 2022:
James Weger-Lucarelli, Ph.D. Assistant Professor, Department of Biomedical Sciences and Pathobiology, VA-MD College of Veterinary Medicine
Title: "SARS-CoV-2 Origins and Threat for Spillover Into Animal Reservoirs" Recorded Video
March 29, 2022:
Townsend Peterson, Ph.D. University Distinguished Professor, Biodiversity Institute, The University of Kansas
Title: "Distributions of Tick Vector Species in the United States: Shifting Distributional Patterns and Transmission Opportunity" Recorded Video
Host: Luis Escobar, Ph.D.
April 5, 2022:
Eva Harris, Ph.D. Professor of Infectious Diseases and Vaccinology, UC Berkeley
Title: "The double-edged sword: Dengue and Zika virus pathogenesis and immunity"
Host: Jonathan Auguste, Ph.D.
April 12, 2022:
Rhoel Dinglasan, Ph.D. Professor of Infectious Diseases and Director of the CDC Southeastern Regional Center of Excellence in Vector Borne Diseases
Title: "Vector-Borne Disease Translational Systems Biology: From discovery to application"
April 19, , 2022:
Stacey Schultz-Cherry, Ph.D. Deputy Director, World Health Organization Collaborating Centre or Studies on the Ecology of Influenza in Animals and Birds,
Title: "Influenza Pathogenesis in Vulnerable Populations"
April 26,, 2022:
Oliver Fregoso, Ph.D. Assistant Professor, Microbiology, Immunology and Molecular Genetics, UCLA
Title: "The DNA Damage response in HIV replication and cure"
Host: Nisha Duggal, Ph.D.
May 3, 2022:
Nancy Keller, Ph.D. Professor of Medical Microbiology and Immunology and Bacteriology, University of Wisconsin-Madison
Title: "Co-opting oxylipin signals in fungal disease"
Host: Rana Ashkar, Ph.D.
Center for Emerging, Zoonotic, and Arthropod-borne Pathogens Journal Club
TUESDAYS 4pm, Starting Feb. 10th, 2022 ( https://virginiatech.zoom.us/j/89884861237)
There will be an Infectious Disease Journal Club each week, on Thursdays, 12:30-1:30 pm. This journal club will be tied to CEZAP seminar series, on Tuesdays. We will discuss a research article by the next week’s speaker.
GOAL. The goal of this journal club is to: introduce participants to research of guest speakers; discuss research and concepts presented in the paper; discuss the paper’s strengths and weaknesses; alternate ways to present information contained within the paper; and alternate approaches to testing hypothesis presented in the article.
FORMAT. The format will be as follows. A facilitator will provide a brief introduction of the paper. Following this introduction, participants will be assigned discussion groups and responsibility for specific Results section or supplemental data. The groups will discuss whether the results support the hypothesis, limitations, uniqueness of the approach, and alternate ways to present the data. A representative from each group will summarize and report on the group’s discussion. The facilitator will report to the group on the author’s interview concerning their challenges, resolution of technical process and insight into the paper’s review. Journal club ends with a general discussion including the impact of the paper, its overall strengths and weaknesses, and what needs to be done next.
DELIVERY. The journal club will start out virtual during the month of February and possibly March, contingent on the current COVID surge. It will move to a hybrid-format: meeting in-person but also providing a virtual connection for participants who cannot physically attend journal club.
REQUIREMENTS. For this to work, participants need to read the assigned paper before the next journal club. It also requires participants to be engaged in paper’s discussion.
Contact John Maurer (firstname.lastname@example.org) if you would like to join and be included on the list serve for this journal club.
PAPERS FOR SPRING 2022 SEMESTER
February 10th Journal Club: “Temporal shifts in antibiotic resistance elements govern phage-pathogen conflicts” (www.science.org/doi/10.1126/science.abg2166?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed).
February 17th Journal Club: “IL-1 reprogramming of adult neural stem cells limits neurocognitive recovery after viral encephalitis by maintaining a proinflammatory state” (www.sciencedirect.com/science/article/pii/S0889159121005869?via%3Dihub)
February 24th Journal Club: “Staffing and capacity planning for SARS-CoV-2 monoclonal antibody infusion facilities: a performance estimation calculator based on discrete-event simulations” (www.frontiersin.org/articles/10.3389/fpubh.2021.770039/full)
March 3rd Journal Club: “Clostridioides difficile Toxin A remodels membranes and mediates DNA entry into cells to activate Toll Like Receptor 9 signaling” (www.sciencedirect.com/science/article/pii/S0016508520351088)
March 10th Journal Club: “A selective sweep in the Spike gene has driven SARS-CoV-2 human adaptation” (www.sciencedirect.com/science/article/pii/S0092867421008333?via%3Dihub)
March 17th Journal Club: “Potential geographic distribution of Ixodes cookie, the vector of Powassan virus” (https://bioone.org/journals/journal-of-vector-ecology/volume-46/issue-2/1081-1710-46.2.155/Potential-geographic-distribution-of-Ixodes-cookei-the-vector-of-Powassan/10.52707/1081-1710-46.2.155.short)
JOURNAL CLUB MOVING TO TUESDAYS AT 4PM AT THE ILSB BUILDING, ROOM 1040
March 22th Journal Club: “Dengue and Zika virus infections in children elicit cross-reactive protective and enhancing antibodies that persist long term” (www.science.org/doi/10.1126/scitranslmed.abg9478)
March 29st Journal Club: “Under-the-radar Dengue Virus infections in natural populations of Aedes aegypti mosquitoes” (journals.asm.org/doi/10.1128/mSphere.00316-20)
April 5th Journal Club: “Human Astroviruses: a tale of two strains” (www.ncbi.nlm.nih.gov/pmc/articles/PMC7997325/)
April 12th Journal Club: “Activation of the DNA damage response is a conserved function of HIV-1 and HIV-2 Vpr that is independent of SLX4 recruitment” (journals.asm.org/doi/10.1128/mBio.01433-16)
April 19st Journal Club: “Transcription factor repurposing offers insights into evolution of biosynthetic gene cluster regulation” (journals.asm.org/doi/10.1128/mBio.01399-21)
Fralin Life Sciences Institute
Virginia Tech Corporate Research Center (CRC)
Integrated Life Science Building (ILSB)
1981 Kraft Dr, Room 2036
Blacksburg, VA 24060
Integrated Life Sciences Building,